• This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.[provided by RefSeq, Feb 2009]
  

BATF3 (Basic Leucine Zipper ATF-Like Transcription Factor 3) is a Protein Coding gene. Diseases associated with BATF3 include Hematologic Cancer and Dendritic Cell Deficiency. Among its related pathways are Calcineurin-regulated NFAT-dependent transcription in lymphocytes and Pre-implantation embryo. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding. An important paralog of this gene is BATF.